Barney Biological Engineering Laboratory Overview

Paramedium bursaria video clip

Research Interests

Our laboratory focuses on four primary research areas. The first focus involves the study of biosynthetic pathways for commodity fuels and high-value products from select bacteria, cyanobacteria and algae. Our second focus is on bacteria and cyanobacteria capable of biological nitrogen fixation (BNF) and the role these species play in the biological nitrogen cycle. Our third focus is related to the production of extracellular fermentable sugars from phototrophs (algae) and our final focus is related to organisms that are capable of biodegrading commodity plastics and other polymers in the environment.

Modern biological engineering includes efforts to utilize genetic on molecular biology tools to enable the synthesis of various biological compounds, also known as synthetic biology. In recent years, the distinctions between various scientific and engineering disciplines have become less stringent as all of these disciplines make use of modern tools that enable the engineering of entire organisms. Members of our laboratory must have a strong microbiology and biochemistry background with an interest in applied and basic science. 

In recent years, we have constructed various tools for genetic approaches in model bacteria, and are interested in biosynthetic approaches to produce compounds that could replace current fuels or have value as specialty chemicals.

Specific Research Projects

  • Biological nitrogen fixation (BNF) for sustainable solutions to agriculture and algal culture
  • Extracellular sugar production by model green algae
  • Wax ester production in the model bacterium Marinobacter aquaeolei VT8
  • Triacylglyceride (TAG) production from alkaline diatoms
  • Identification of microbes capable of biodegrading polyethylene and polystyrene
  • Directed evolution approaches for novel protein design and pathway engineering

News

New Publication

Our latest paper "A foundation for advancing studies of the biodegradation of polyethylene surrogates by environmental and model laboratory microbes" is now published in Environmental Microbiology Reports.

New Publication

Our paper "Azotobacter vinelandii gene fitness following carbon shift from sucrose to acetate, succinate and glycerol" is now published in Microbiology.

Bahar successfully defends her dissertation

Congratulations to Bilge Bahar Camur for successfully defending her PhD dissertation titled "Harnessing Environmental and Engineered Microbes for Polyethylene Surrogate Degradation and Sustainable Bio-Oil &Wax Production". Bahar published two first-author papers, and one contributing author paper. Congratulations Bahar.